2017 European league against rheumatism/American College of Rheumatology classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups. Lundberg IE, Tjarnlund A, Bottai M, et al. 119th ENMC international workshop: trial design in adult idiopathic inflammatory myopathies, with the exception of inclusion body myositis, 10–12 October 2003, Naarden, The Netherlands. Hoogendijk JE, Amato AA, Lecky BR, et al. Polymyositis and dermatomyositis (second of two parts). Polymyositis and dermatomyositis (first of two parts). In the last decade, new IIM classification systems based on extensive clinical data collection, new pathological development, and discovery of myositis-specific autoantibodies (MSA) have been proposed.īohan A, Peter JB. Inevitably, diagnostic discrepancies and heterogenous treatment outcomes within the same IIM subgroups occur as a result of limitations of classifications and divergent diagnostic approaches, mainly between clinically oriented and pathologically oriented physicians. These historical classifications, however, contain overlapping clinical and pathological criteria. Various classification systems based on experts’ opinions were also proposed. In 2003, the European Neuromuscular Centre (ENMC) international workshop (2003 ENMC–IIM) revised dermatomyositis and polymyositis classification and proposed two additional categories, immune-mediated necrotizing myopathy (IMNM) and nonspecific myositis to further subclassify IIM according to possible different pathogenesis. Until recently, IIM had been widely classified into three major subgroups including polymyositis and dermatomyositis using the 1975 Bohan and Peter classification and inclusion body myositis (sIBM) using the 1995 Griggs et al. They are collectively characterized by various degrees of muscle weakness and inflammation associated with a different spectrum of extra-muscular manifestations. Idiopathic inflammatory myopathies (IIM) are composed of heterogeneous subgroups of neuromuscular disorders generally known as myositis.
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